Another historic first: Utah is playing its first conference game as a member of the Pac-12, and it comes at USC.
Big games in the SEC - Mississippi State at Auburn and South Carolina at Georgia - also bear watching.
Arizona (1-0) at Oklahoma State (1-0), 8 p.m., ESPN THE BUZZ: These teams met in the Alamo Bowl to end last season, and Oklahoma State rolled 36-10. Two of the nation's best pass-catch combinations will be on view with Arizona's Nick Foles and Juron Criner and Oklahoma State's Brandon Weeden and Justin Blackmon. This is the beginning of a brutal stretch for Arizona, which plays Stanford, Oregon and USC in its next three games.
THE LINE: Oklahoma State by 14 THE PICK: Oklahoma State 41-31
Florida International (1-0) at Louisville (1-0), 7 p.m., ESPN THE BUZZ: Big East teams are a combined 21-0 against Sun Belt teams, but this looks to be a dangerous game for Louisville, which sputtered on offense against FCS member Murray State last week. FIU WR T.Y. Hilton had 283 all-purpose yards against North Texas last week, the highest total in the nation.
THE LINE: Louisville by 4 THE PICK: Louisville 23-20
Missouri (1-0) at Arizona State (1-0), 10:30 p.m., ESPN THE BUZZ: This might be the best game of the weekend. Both teams expect to contend for their league title, but both have some issues. Mizzou sputtered offensively in beating Miami (Ohio) last week. Arizona State's defense is stout, but can QB Brock Osweiler get the job done against good opponents? Arizona State will debut its all-new black helmets and uniforms.
THE LINE: Arizona State by 7.5 THE PICK: Arizona State 22-17
Oregon State (0-1) at Wisconsin (1-0), noon, ESPN2 THE BUZZ: The Beavers are coming off a shocking OT loss to FCS member Sacramento State and seem likely to start 0-2 for the second time in four seasons. Wisconsin has won 29 consecutive regular-season non-conference games; that's the second-longest streak of that nature nationally, behind LSU's 34. Wisconsin offensive coordinator Paul Chryst spent a total of nine seasons as an assistant to Oregon State coach Mike Riley with the Beavers, the NFL's San Diego Chargers and the World League's San Antonio Riders.
THE LINE: Wisconsin by 21.5 THE PICK: Wisconsin 40-21
Florida Atlantic (0-1) at Michigan State (1-0), noon, ESPN THE BUZZ: This is the third meeting in the series, and all the games have come since 2008. Michigan State senior WR B.J. Cunningham has 148 career receptions, which ties him with Matt Trannon for the most in school history.
THE LINE: Michigan State by 32.5 THE PICK: Michigan State 45-10
Toledo (1-0) at Ohio State (1-0), noon, Big Ten Network
THE BUZZ: This is just the third meeting between the in-state schools, and Ohio State has won both -- by a combined 87-0. Ohio State is 17-0 all-time against MAC schools and hasn't lost to a school from Ohio since falling 7-6 to Oberlin in 1921. Toledo, which is coached by former Ohio State assistant Tim Beckman, is seeking its first 2-0 start since 2005.
THE LINE: Ohio State by 19 THE PICK: Ohio State 35-14
Iowa (1-0) at Iowa State (1-0), noon, Fox Sports Net THE BUZZ: These teams play for the Cy-Hawk Trophy; a new trophy was unveiled this year, but it met with such disapproval that it was scrapped before it was awarded even once. Just call it the "Children of the Corn Classic" and be done with it. In the series, Iowa has won three in a row, four of five, six of eight and 21 of 28.
THE LINE: Iowa by 6.5 THE PICK: Iowa 27-17
Central Michigan (1-0) at Kentucky (1-0), noon, ESPNU THE BUZZ: Central Michigan is 0-7 all-time against SEC schools, with five of the losses coming to UK. CMU is looking for its first 2-0 start since 2002. The Wildcats are looking for their fifth consecutive 2-0 start. This is one of just three games CMU will play on real grass this season.
THE LINE: Kentucky by 12.5 THE PICK: Kentucky 21-10
San Diego State (1-0) at Army (0-1), noon, CBS Sports Network THE BUZZ: This is the longest road trip for any team not involving a game with Hawaii. The Aztecs' campus is roughly 2,425 miles from Army's. While Army's triple option can be tough to stop, the Black Knights gave up 289 rushing yards to Northern Illinois last week; that has to make Aztecs TB Ronnie Hillman -- who has rushed for at least 150 yards in seven of his 14 career games -- mighty happy.
THE LINE: San Diego State by 9.5 THE PICK: San Diego State 33-21
South Dakota State (1-0) at Illinois (1-0), noon, Big Ten Network THE BUZZ: The Illini have five consecutive home games to begin the 2011 season and eight total home games for the first time since 1903, when Illinois played nine home games. Illinois was one of three FBS teams last week not to be called for a penalty (Eastern Michigan and Navy were the others). That was the first time in 18 years that the Illini didn't commit a penalty.
THE LINE: None THE PICK: Illinois 44-17
Mississippi State (1-0) at Auburn (1-0), 12:20 p.m., SEC syndication/Altitude/MSG network/Comcast Sports Net California/ESPN GamePlan THE BUZZ: Auburn has won 17 of its past 18 SEC openers, has won 16 in a row overall and has won nine in a row at home. Auburn also has won nine of the past 10 against the Bulldogs. Mississippi State has scored at least 30 points in four consecutive games; that's the longest such streak in school history.
THE LINE: Mississippi State by 7 THE PICK: Mississippi State 24-20
Rutgers (1-0) at North Carolina (1-0), 12:30 p.m., ACC syndication/Sportsnet New York/ESPN GamePlan THE BUZZ: Both had easy wins over FCS opponents last week. This is the second of six ACC/Big East games this season; the Big East leads 1-0.
THE LINE: UNC by 10.5 THE PICK: UNC 27-21
Norfolk State (1-0) at West Virginia (1-0), 1 p.m., Big East syndication/ESPN GamePlan THE BUZZ: WVU opens the season with five of its first six at home. Norfolk State, an FCS school, is coached by WVU alum Pete Adrian (class of 1970). Adrian also is a former WVU assistant. It's the second week in a row WVU has played a team coached by an alum; last week, the Mountaineers beat Marshall, which is led by Doc Holliday (class of 1979).
THE LINE: None THE PICK: WVU 52-14
Maine (1-0) at Pittsburgh (1-0), 1 p.m. THE BUZZ: Pitt is looking for just its second 2-0 start in the past four seasons. The Panthers have Iowa and Notre Dame in the next two weeks.
THE LINE: None THE PICK: Pitt 51-17
Alabama State (1-0) at Eastern Michigan (1-0), 1 p.m. THE BUZZ: This is the second FCS opponent in a row for Eastern Michigan; last week's win over Howard was the first home-field victory for third-year Eagles coach Ron English. EMU is seeking its first 2-0 start since 1989, Alabama State is coached by former NFL wide receiver Reggie Barlow, who is a Hornets alum.
THE LINE: None THE PICK: Eastern Michigan 27-13
Northern Colorado (0-1) at Colorado State (1-0), 2 p.m., The Mtn. THE BUZZ: This is the 18th meeting between these teams, but the first since 1986. Colorado State leads the series 16-0-1, with the tie coming in the first meeting in 1899. Colorado State is aiming for just its third 2-0 start since 2002.
THE LINE: None THE PICK: Colorado State 38-14
TCU (0-1) at Air Force (1-0), 3:30 p.m., Versus THE BUZZ: TCU, which hasn't started 0-2 since 1999, has won seven of the past eight in this series and has won eight consecutive Mountain West road games. Air Force's defense was gashed for 184 rushing yards by FCS member South Dakota State last week.
THE LINE: TCU by 2 THE PICK: TCU 30-24
Alabama (1-0) at Penn State (1-0), 3:30 p.m., ABC, 3:30 p.m. THE BUZZ: This is the 15th meeting overall and the first in Happy Valley since 1989; the Tide won 24-3 last season in Tuscaloosa. Alabama and Penn State are among just eight FBS teams nationally that have 800 victories. Penn State, in its 125th season, has 819 wins to rank sixth in victories. In its 120th season, Alabama has 803 victories, which ranks eighth.
THE LINE: Alabama by 10 THE PICK: Alabama 20-7
Nevada (0-0) at Oregon (0-1), 3:30 p.m., FX THE BUZZ: Nevada, which won 13 games last season, plays its first four games this season on the road. The Wolf Pack has a six-game winning streak in regular-season non-conference play. Oregon has a 16-game home winning streak.
THE LINE: Oregon by 26.5 THE PICK: Oregon 48-24
Cincinnati (1-0) at Tennessee (1-0), 3:30 p.m., ESPN2 THE BUZZ: Cincinnati scored 72 points against a team from Tennessee (Austin Peay) last week; it will be a wee bit tougher for the Bearcats this week. The Vols play at Florida next week. This is one of two Big East/SEC matchups this weekend and one of four this season.
THE LINE: Tennessee by 6 THE PICK: Tennessee 28-20
Virginia Tech (1-0) at East Carolina (0-1), 3:30 p.m., Fox Sports Net THE BUZZ: From the "that's hard to believe" department: Virginia Tech is aiming for its first 2-0 start since 2001. Since joining the ACC, the Hokies are 12-1 in games played in North Carolina -- with the only loss to ECU in Charlotte in the 2008 opener. ECU QB Dominique Davis was Boston College's starter against Virginia Tech in the 2008 ACC championship game. He left BC after that season and played at a junior college in 2009, then signed with ECU before last season.
THE LINE: Virginia Tech by 20 THE PICK: Virginia Tech 52-28
Stanford (1-0) at Duke (0-1), 3:30 p.m., ESPNU THE BUZZ: This looks like a mismatch. Let's make it interesting by using the following format to determine the winner: The team captains meet at midfield and debate British philosopher Thomas Hobbes' premise posited in his book "Leviathan" that says people are naturally wicked and thus cannot be trusted to govern.
THE LINE: Stanford by 21 THE PICK: Stanford 49-17
Purdue (1-0) at Rice (0-1), 3:30 p.m., CBS Sports Network THE BUZZ: A Big Ten team (Northwestern) played at Rice last season and pounded the Owls. But this Purdue team isn't that good, and Rice's offense is going to cause some issues for the Boilermakers' defense. Purdue blocked a last-play field-goal attempt by Middle Tennessee last week at home to avoid overtime.
THE LINE: Purdue by 1 THE PICK: Purdue 31-27
California (1-0) at Colorado (0-1), 3:30 p.m., Fox College Sports/Comcast Sports Net California THE BUZZ: OK, bear with us for this one. This matches two Pac-12 teams, but it is not a league game. Cal crushed the Buffs 52-7 last season in the first game of a two-game series; the series was signed before Colorado joined the Pac-12. Neither team could find a suitable replacement for this date on the schedule, so it was decided they would play anyway but not count the game in the league standings.
THE LINE: California by 6.5 THE PICK: California 28-17
N.C. State (1-0) at Wake Forest (0-1), 3:30 p.m., ACC syndication/Fox Sports South/Sun Sports/Prime Ticket/NESN/ESPN GamePlan THE BUZZ: NC State fancies itself an ACC contender and ACC contenders don't lose to Wake, even on the road. This is the 103rd meeting in the series and the 102nd consecutive season it has been played, making it the longest continuous rivalry in the league and the third-longest in the nation (behind Kansas-Nebraska at 105 and Minnesota-Wisconsin at 104).
THE LINE: NC State by 2 THE PICK: NC State 34-24
Southern Miss (1-0) at Marshall (0-1), 3:30 p.m., Comcast-Charter Sports Southeast THE BUZZ: This is the C-USA opener for both. Southern Miss QB Austin Davis last week set a school career record with his 23rd 200-yard passing game. He is 74 yards away from unseating Brett Favre (7,695 yards) as the school's career leader.
THE LINE: Southern Miss by 7.5 THE PICK: Southern Miss 31-17
Eastern Illinois (1-0) at Northwestern (1-0), 3:30 p.m., Big Ten Network THE BUZZ: Northwestern is looking for its fifth consecutive 2-0 start. This is the first meeting between the in-state schools, and Eastern Illinois is 0-5 all-time against Big Ten opponents. This is the final season for EIU coach Bob Spoo, who is in his 25th season as the Panthers' coach and his 50th season overall as a coach (high school and college).
THE LINE: None THE PICK: Northwestern 38-14
New Mexico State (0-1) at Minnesota (0-1), 3:30 p.m., Big Ten Network THE BUZZ: New Mexico State, which rushed for 6 yards in last week's loss to Ohio U., has lost 12 road games in a row. New Mexico State coach DeWayne Walker played cornerback at Minnesota from 1980-81. This is the first of three consecutive home games for Minnesota and the first home game for new Gophers coach Jerry Kill.
THE LINE: Minnesota by 20 THE PICK: Minnesota 44-20
Hawaii (1-0) at Washington (1-0), 3:30 p.m., ROOT Sports Northwest/Fox College Sports Atlantic THE BUZZ: Washington had to hold on for dear life last week against FCS member Eastern Washington, winning 30-27 when a last-minute pass was picked off in the end zone. The Huskies allowed 473 passing yards to EWU. That should make defensive coordinator Nick Holt shudder with pass-happy Hawaii next on the schedule. Hawaii beat Colorado last week and looks to go 2-0 vs. the Pac-12 this season.
THE LINE: Washington by 6.5 THE PICK: Washington 31-27
Tulsa (0-1) at Tulane (1-0), 3:30 p.m. THE BUZZ: This is the only respite in Tulsa's extremely difficult season-opening month. The Golden Hurricane opened with a loss last week at Oklahoma; they play host to Oklahoma State next week before traveling to Boise State on Sept. 24. Tulsa has won six in a row in the series and has outscored Tulane 45-13 on average in those victories.
THE LINE: Tulsa by 13.5 THE PICK: Tulsa 45-20
Wofford (1-0) at Clemson (1-0), 3:30 p.m. THE BUZZ: This is the 14th meeting in the series between the schools, whose campuses are less than an hour apart. This is the second of four consecutive home games to open the season for Clemson.
THE LINE: None THE PICK: Clemson 45-13
South Carolina (1-0) at Georgia (0-1), 4:30 p.m., ESPN THE BUZZ: A big early-season game in the SEC East, as the winner becomes the team to beat in the division. In other words, Georgia can erase almost all the bad feelings emanating from last week's loss to Boise State with a victory between the hedges. Georgia has won seven of the past 10 in the series. South Carolina won last season and is looking for back-to-back wins over the Bulldogs for the first time since 2000 and '01.
THE LINE: South Carolina by 2.5 THE PICK: South Carolina 21-16
Rhode Island (0-0) at Syracuse (1-0), 4:30 p.m., Big East syndication/Sportsnet New York/ESPN GamePlan THE BUZZ: This looks like a gimme for the Orange. The Colonial Athletic Association could be considered the SEC of the FCS ranks; in that case, Rhode Island is the CAA's Vanderbilt. The Rams have finished with a losing record in 14 of the past 15 seasons and 22 of the past 25.
THE LINE: None THE PICK: Syracuse 44-14
North Dakota (1-0) at Idaho (0-1), 5 p.m. THE BUZZ: This is the second meeting between the schools; Idaho won 45-0 last season. This is the first season as a full-fledged FCS member for North Dakota; the Fighting Sioux had been transitioning from Division II the past two seasons.
THE LINE: None THE PICK: Idaho 40-21
UNLV (0-1) at Washington State (1-0), 5 p.m. THE BUZZ: It's fitting that this is not on TV, as it's our dog of the week. (Frankly, the hounds better be on the road by now because Pullman can be hard to get to.) These programs have combined for 45 wins in the past seven seasons, and Washington State hasn't started 2-0 since 2005.
THE LINE: Washington State by 14 THE PICK: Washington State 34-17
Stony Brook (0-1) at Buffalo (0-1), 6 p.m., ESPN GamePlan THE BUZZ: This is the second FBS opponent in a row for Stony Brook, a FCS school on Long Island that lost in overtime at UTEP last week. This is the third consecutive season Buffalo is playing host to a FCS opponent; the Bulls beat Rhode Island 31-0 last season and routed Gardner-Webb 40-3 in 2009.
THE LINE: None THE PICK: Buffalo 28-20
Texas State (0-1) at Wyoming (1-0), 6 p.m., The Mtn. THE BUZZ: This is the second FCS opponent in a row for Wyoming, which scored in the final minute to nip Weber State last week. Texas State coach Dennis Franchione went 1-3 against Wyoming when he coached at Mountain West schools TCU and New Mexico.
THE LINE: None THE PICK: Wyoming 30-21
Southern Illinois (1-0) at Ole Miss (0-1), 6 p.m., ESPN GamePlan THE BUZZ: While Ole Miss hasn't started 0-2 since 2004, Rebels coach Houston Nutt hasn't started 0-2 since 1993, when he was in his first season as coach at Murray State. This is the second of four consecutive home games to open the season for Ole Miss, which plays six of its first seven at home and has eight total home games. Iowa transfer Jewel Hampton is SIU's backup tailback.
THE LINE: None THE PICK: Ole Miss 30-14
Charleston Southern (0-1) at Florida State (1-0), 6 p.m. THE BUZZ: Oh, the humanity. Charleston Southern is coming off a 62-0 loss at UCF; the Bucs have played 10 games against FBS opponents in their history and have been outscored 565-88. FSU coach Jimbo Fisher has to tread the fine line of making sure his starters get in enough work for next week's showdown against Oklahoma but also be wary of making sure this doesn't get too out of hand.
THE LINE: None THE PICK: FSU 70-6
Temple (1-0) at Akron (0-1), 6 p.m. THE BUZZ: This is the MAC opener for both. Temple is trying to open 2-0 for the second consecutive season. The last time the Owls started 2-0 in two seasons in a row? Try 1967 and '68. The Owls have beaten the Zips in each of the past four seasons, by a combined 137-43.
THE LINE: Temple by 15 THE PICK: Temple 35-17
BYU (1-0) at Texas (1-0), 7 p.m., ESPN2 THE BUZZ: This is the third meeting between the teams, and BYU is 2-0 (wins in 1987 and '88; the Cougars forced a school-record eight turnovers in '87). This is the second home game for Texas, which plays each of its next three away from home. The Longhorns ran the ball effectively last week against Rice; can they do so against BYU?
THE LINE: Texas by 7 THE PICK: Texas 24-14
UAB (0-0) at Florida (1-0), 7 p.m., Fox Sports Florida/Fox Sports South/ESPN GamePlan THE BUZZ: UAB becomes the final FBS team to open its season; Nevada also was off last week but it plays Oregon on Saturday afternoon. These teams have met once, with Florida winning 51-3 in 2002 in Ron Zook's first game as the Gators' coach.
THE LINE: Florida by 23 THE PICK: Florida 38-17
UTEP (1-0) at SMU (0-1), 7 p.m., Fox Sports Net THE BUZZ: This is the C-USA opener for both. UTEP, which beat FCS member Stony Brook in OT last week, has won six of the past eight meetings, and three of the past four games at SMU have been decided by four or fewer points. UTEP is 5-19 on the road in C-USA play since joining the league in 2005.
THE LINE: SMU by 20 THE PICK: SMU 49-24
Fresno State (0-1) at Nebraska (1-0), 7 p.m., Big Ten Network THE BUZZ: Fresno State has lost 12 consecutive games to top-25 opponents. But the Bulldogs have won seven of their past 11 against Big Six schools. This is the first game in a three-game series between the schools. Nebraska will travel to Fresno in 2014, and the Bulldogs return to Lincoln in 2016.
THE LINE: Nebraska by 28 THE PICK: Nebraska 35-10
New Mexico (0-1) vs. Arkansas (1-0) in Little Rock, 7 p.m., ESPNU THE BUZZ: New Mexico allowed nine sacks in losing to Colorado State last week. This is the third meeting between these teams, and all three have been in Little Rock. Arkansas has thrown at least one TD pass in 18 consecutive games, the longest active streak in the SEC and tied for the sixth-longest active streak in the country.
THE LINE: Arkansas by 36 THE PICK: Arkansas 57-14
Ball State (1-0) at USF (1-0), 7 p.m., Big East syndication/Altitude2/ESPN GamePlan THE BUZZ: This is the 15th season of football for USF, and the Bulls never have lost a home opener. They've dropped two home games in a row and never have lost three in a row at home. This is the second consecutive game in an NFL stadium for Ball State, which upset Indiana last week at Indianapolis' Lucas Oil Stadium.
THE LINE: USF by 20 THE PICK: USF 35-17
Northern Illinois (1-0) at Kansas (1-0), 7 p.m., Fox College Sports THE BUZZ: NIU is looking to go 2-0 for the first time since 2003, when the Huskies finished 10-2. New NIU coach Dave Doeren is a Kansas native who was a Jayhawks assistant from 2002-05 under Mark Mangino. This is the only non-conference road game for NIU. KU has won 23 of its past 25 non-conference home games.
THE LINE: NIU by 6.5 THE PICK: NIU 31-20
Virginia (1-0) at Indiana (0-1), 7 p.m., Big Ten Network THE BUZZ: Indiana is coming in off a loss to Ball State, while Virginia never has won a true road game against a Big Ten team (0-3). These teams played at Virginia in 2009 and the Cavs won by 40. This is one of three ACC/Big Ten matchups this season, and the Big Ten already leads 1-0.
THE LINE: Virginia by 6.5 THE PICK: Virginia 33-24
Navy (1-0) at Western Kentucky (0-1), 7 p.m. THE BUZZ: This is the first of three consecutive home games for WKU. A victory would give Navy coach Ken Niumatalolo his 29th career win, which would be the most in school history for a coach in his first four years at the Academy. He is tied with Paul Johnson, who was 28-21 in his first four seasons.
THE LINE: Navy by 9.5 THE PICK: Navy 38-20
Morgan State (0-1) at Bowling Green (1-0), 7 p.m. THE BUZZ: Bowling Green hasn't started 2-0 since 2003. The Falcons have 22 non-conference wins since 2001, the most in the MAC. This is one of four games this weekend in which a MAC school plays a FCS opponent.
THE LINE: None THE PICK: Bowling Green 40-14
Gardner-Webb (1-0) at Ohio (1-0), 7 p.m. THE BUZZ: Ohio coach Frank Solich is going for his 100th career victory. A win also would give the Bobcats their first 2-0 start since 2007.
THE LINE: None THE PICK: Ohio 41-17
Houston (1-0) at North Texas (0-1), 7 p.m. THE BUZZ: You want to know why Houston could be a BCS-buster? Each of the Cougars' first 10 games this season is against a team that had a losing record last season. This is the first game at Apogee Stadium, a 30,850-seat on-campus stadium that cost $75 million.
THE LINE: Houston by 22.5 THE PICK: Houston 51-27
Memphis (0-1) at Arkansas State (0-1), 7 p.m. THE BUZZ: This is the 56th meeting between schools whose campuses are about an hour apart. Arkansas State has lost eight consecutive non-conference games, while Memphis has lost 10 in a row overall.
THE LINE: Arkansas State by 15 THE PICK: Arkansas State 35-21
Louisiana-Lafayette (0-1) at Kent State (0-1), 7 p.m. THE BUZZ: These teams first met in 2008, with ULL coming away with the home win. Two of the better non-Big Six players nationally will be in this game: ULL TE Ladarius Green and Kent State DT Roosevelt Nix. ULL is 0-4 all-time in games at MAC stadiums.
THE LINE: Kent State by 9.5 THE PICK: Kent State 23-17
Central Arkansas (1-0) at Louisiana Tech (0-1), 7 p.m. THE BUZZ: True freshman QB Nick Isham, who is just 17, started last week for Louisiana Tech; he is the second-youngest quarterback in college football history to start the first game of his career (Texas A&M's David Walker started the 1973 opener; he was a month and a day younger than Isham.) Central Arkansas' quarterback is Arkansas transfer Nathan Dick.
THE LINE: None THE PICK: Louisiana Tech 27-16
Georgia Tech (1-0) at Middle Tennessee (0-1), 7 p.m. THE BUZZ: Tech pounded MTSU in Atlanta last season, and this is the Yellow Jackets' first road game at a non-Big Six school since it played at BYU in 2003. This is one of just three games this season in which a Big Six school plays at a Sun Belt school. Yellow Jackets linebacker coach Andy McCollum was MTSU's coach from 1999-2005.
THE LINE: Georgia Tech by 11 THE PICK: Georgia Tech 45-27
Grambling (1-0) at Louisiana-Monroe (0-1), 7 p.m. THE BUZZ: Doug Williams, a Grambling alum, is in his second go-round as the Tigers' coach. This is just the second meeting between the schools, whose campuses are about 40 miles apart in northeast Louisiana. The other game came in 2007, when ULM set an attendance record with 30,101 fans.
THE LINE: None THE PICK: ULM 27-14
Nicholls State (1-0) at Western Michigan (0-1), 7 p.m. THE BUZZ: Nicholls State, a FCS program from Thibodaux, La., opened with a win over NAIA program Evangel (Mo.) last week. Nicholls is coached by former Alabama and Tulsa offensive coordinator Charlie Stubbs. These teams met last season, and WMU won by 35.
THE LINE: None THE PICK: Western Michigan 45-16
Utah (1-0) at USC (1-0), 7:30 p.m., Versus THE BUZZ: This is the Utes' first league game as a Pac-12 member and it comes against the most storied program in Pac-8/Pac-10 history. Neither team was all that impressive in its opener. This is the 10th meeting between the schools, though just the third since 1948. Utah won the last meeting, in the 2001 Las Vegas Bowl.
THE LINE: USC by 9.5 THE PICK: USC 24-17
Connecticut (1-0) at Vanderbilt (1-0), 7:30 p.m., Comcast-Charter Sports Southeast/Sportsnet New York/ESPN GamePlan THE BUZZ: This might match the worst team in the Big East against the worst team in the SEC. Vandy is going for just its third 2-0 start since 1993. A victory would mean UConn coach Paul Pasqualoni would become the winningest coach in Big East history; he has 108 victories, which ties him with Virginia Tech's Frank Beamer.
THE LINE: Vandy by 2 THE PICK: UConn 17-13
Notre Dame (0-1) at Michigan (1-0), 8 p.m., ESPN THE BUZZ: This will be the first night game in the 84-year history of Michigan Stadium. It also represents the first of a school-record five night games for Notre Dame in 2011. The Wolverines have won five of their past six games against the Irish in Ann Arbor and four of the past five overall.
THE LINE: Notre Dame by 3.5 THE PICK: Notre Dame 30-24
Boston College (0-1) at UCF (1-0), 8 p.m., CBS Sports Network THE BUZZ: Boston College is the 11th Big Six program to play at UCF -- and the Knights have lost all 10 prior games. BC was without star TB Montel Harris in last week's loss to Northwestern, and could be without him again this week. UCF snapped a 10-game overall losing streak to Big Six opponents with a Liberty Bowl victory over Georgia last season.
THE LINE: UCF by 7 THE PICK: UCF 20-17
Northwestern State (La.) (1-0) at LSU (1-0), 8 p.m., ESPN GamePlan THE BUZZ: LSU played Oregon last week and the Tigers travel to Mississippi State next Thursday, so forgive them if they come out and scuffle around against their FCS foe. These teams haven't played since 1942, and it's a Super Bowl of sorts for the Delta Demons, who will dress out 115 players and bring their band. Northwestern State is one win shy of 500 in its history. It's a safe bet the win won't come in Baton Rouge.
THE LINE: None THE PICK: LSU 51-7
Weber State (0-1) at Utah State (0-1), 8 p.m. THE BUZZ: Both lost in the final minute last week - Weber State at Wyoming and Utah State at Auburn. These in-state foes have met 12 times, and Weber's only win came in 1978. Utah State coach Gary Andersen played center at Utah in 1985-86, when Weber coach Ron McBride was the Utes' offensive line coach. Andersen also served as an assistant for McBride at Utah from 1997-2002.
THE LINE: None THE PICK: Utah State 38-23
San Jose State (0-1) at UCLA (0-1), 10 p.m., Fox Sports West THE BUZZ: Surprisingly, this is the first meeting between the schools. In fact, UCLA is the only Pac-12 team San Jose State never has played. San Jose State has lost 11 in a row, the longest active streak in the nation, and 15 in a row on the road, tied for the third-longest streak in the country.
THE LINE: UCLA by 21.5 THE PICK: UCLA 42-17
71-7 straight up, 21-19 against the spread (no spread on games involving FCS schools).
Mike Huguenin is the college sports editor for Rivals.com. He can be reached at firstname.lastname@example.org.